Dual-Gene Delivery Strategy Shows Promise Against Aggressive Brain Cancer

Post Views: 934 Dual-Gene Delivery Strategy Shows Promise Against Aggressive Brain Cancer Glioblastoma is one of the most aggressive and difficult-to-treat forms of brain cancer. Even with surgery, radiation, and chemotherapy, survival rates remain limited. One major challenge is that glioblastoma tumors are highly invasive and adapt quickly, often resisting standard treatments. At the same time, the brain’s protective…

Population-Specific Genomic Data Improves Disease Risk Prediction in the Taiwanese Han Population

Post Views: 785 Population-Specific Genomic Data Improves Disease Risk Prediction in the Taiwanese Han Population Modern medicine increasingly aims to predict disease risk before symptoms appear. Advances in genomic research have enabled the identification of genetic variants associated with conditions such as diabetes, cardiovascular disease, and kidney disorders. Yet a major limitation remains: most large-scale genetic studies have been conducted primarily…

A Precision Peptide Improves Stem Cell Targeting and Tissue Regeneration

Post Views: 1,293 A Precision Peptide Improves Stem Cell Targeting and Tissue Regeneration Regenerative medicine promises to repair tissues that the body struggles to heal on its own, such as damaged cartilage in joints or corneal injuries. Yet despite years of progress in stem cell research, one persistent challenge remains: precision. When stem cells are introduced into…

How Cosmic Dust, Solar Wind, and Impacts Quietly Reshape the Surfaces of the Moon, Mars

Post Views: 2,311 How Cosmic Dust, Solar Wind, and Impacts Quietly Reshape the Surfaces of the Moon, Mars  Recent research carried out by research team led by Prof. Xiaoping Zhang at Macau University of Science and Technology (MUST) has examined how planetary surfaces evolve under the influence of the space environment. Through studies of lunar samples, meteorites,…

Decoding Diversified Plant Polysaccharides for Health Support and Advanced Applications

Post Views: 161 Decoding Diversified Plant Polysaccharides for Health Support and Advanced Applications  Plant polysaccharides are among the most abundant natural polymers found in medicinal and edible plants. However, their high molecular weights and complex branching structures often make them difficult to decipher.   Recent research has shown that high–molecular-weight glucans isolated from Gastrodia elata possess well-defined backbone and branching structures even at the million-Da scale [1]. Through advanced structural characterization and molecular dynamics simulations, these large…

The Chemistry We’ve Been Missing: LC–MS-based Metabolomics Strategies to Reveal Hidden Health Signals

Post Views: 168 The Chemistry We’ve Been Missing: LC–MS-based Metabolomics Strategies to Reveal Hidden Health Signals Inside our bodies, and inside fruits and medicinal plants, thousands of tiny molecules reflect what is happening in real time. These molecules, called metabolites, can reveal early signs of cancer, infection, mental health imbalance, or nutritional function.    However, many of…

Blocking a Tumor’s Protective Signal Strengthens Immune Defense

Post Views: 1,221 Blocking a Tumor’s Protective Signal Strengthens Immune Defense Triple-negative breast cancer (TNBC) is among the most challenging forms of breast cancer to treat. Unlike other subtypes, it lacks hormone receptors and HER2 expression, leaving fewer targeted therapy options available. Although immunotherapy has shown promise in some patients, many TNBC tumors create a…

Ether-Lipid Accumulation Linked to Faster Progression of Liver Cancer

Post Views: 1,184 Ether-Lipid Accumulation Linked to Faster Progression of Liver Cancer Liver cancer, particularly hepatocellular carcinoma (HCC), is often associated with chronic metabolic stress, including fatty liver disease and long-term inflammation. As researchers continue to uncover how cancer cells rewire their metabolism to survive and spread, attention has increasingly turned toward lipids, molecules once considered passive…

Seeing Disease Earlier, Faster, and More Clearly

Post Views: 2,776 Seeing Disease Earlier, Faster, and More Clearly Modern medicine produces vast amounts of data, yet many clinical decisions are still made only after disease becomes visible or irreversible. Prof. Zhang Kang’s research team at the Macau University of Science and Technology is working toward a different paradigm: identifying meaningful biological change earlier, interpreting complex…

A Newly Identified DNA Repair Switch Drives Resistance to PARP Inhibitors in Breast Cancer

Post Views: 888 A Newly Identified DNA Repair Switch Drives Resistance to PARP Inhibitors in Breast Cancer Targeted cancer therapies are designed to exploit specific weaknesses in tumor cells. One such treatment, PARP inhibitors, has transformed care for patients with breast cancers carrying BRCA mutations. These drugs work by blocking a DNA repair protein called…