Post Views: 157 The Chemistry We’ve Been Missing: LC–MS-based Metabolomics Strategies to Reveal Hidden Health Signals Inside our bodies, and inside fruits and medicinal plants, thousands of tiny molecules reflect what is happening in real time. These molecules, called metabolites, can reveal early signs of cancer, infection, mental health imbalance, or nutritional function. However, many of…
Post Views: 1,213 Blocking a Tumor’s Protective Signal Strengthens Immune Defense Triple-negative breast cancer (TNBC) is among the most challenging forms of breast cancer to treat. Unlike other subtypes, it lacks hormone receptors and HER2 expression, leaving fewer targeted therapy options available. Although immunotherapy has shown promise in some patients, many TNBC tumors create a…
Post Views: 1,178 Ether-Lipid Accumulation Linked to Faster Progression of Liver Cancer Liver cancer, particularly hepatocellular carcinoma (HCC), is often associated with chronic metabolic stress, including fatty liver disease and long-term inflammation. As researchers continue to uncover how cancer cells rewire their metabolism to survive and spread, attention has increasingly turned toward lipids, molecules once considered passive…
Post Views: 2,708 Seeing Disease Earlier, Faster, and More Clearly Modern medicine produces vast amounts of data, yet many clinical decisions are still made only after disease becomes visible or irreversible. Prof. Zhang Kang’s research team at the Macau University of Science and Technology is working toward a different paradigm: identifying meaningful biological change earlier, interpreting complex…
Post Views: 880 A Newly Identified DNA Repair Switch Drives Resistance to PARP Inhibitors in Breast Cancer Targeted cancer therapies are designed to exploit specific weaknesses in tumor cells. One such treatment, PARP inhibitors, has transformed care for patients with breast cancers carrying BRCA mutations. These drugs work by blocking a DNA repair protein called…
Post Views: 619 Lithium-Enhanced Bone Scaffold Promotes Immune-Guided Bone Regeneration Repairing damaged bone is not simply a matter of filling a structural gap. Successful bone healing depends on a carefully orchestrated interaction between immune cells, blood vessels, and bone-forming cells. When bone is injured, immune cells such as macrophages arrive first. Initially, they trigger inflammation…
Post Views: 1,252 Engineered Hydrogel Enhances Diabetic Wound Healing by Modulating Immune Response Chronic wounds are among the most challenging complications faced by people living with diabetes. Unlike normal injuries that heal in a predictable sequence, diabetic wounds often remain trapped in prolonged inflammation. Poor blood circulation, oxidative stress, and impaired collagen formation prevent proper…
